Rodent Blood Pressure and Flow Measurement Workshop

Rene Remie Geen categorie

Transonic and the René Remie Surgical Skills Centre (RRSSC) join forces during this rodent microsurgery, blood pressure and flow workshop. This is an on-demand fully customizable workshop that will make you an expert in your rodent blood pressure and flow application of choice. Workshop Goal: The goal of this workshop is to teach registrants all ins and outs of solid-state pressure technology and ultrasound transit-time-based absolute volume blood flow measurements while optimizing their microsurgical skills. Since the number of applications in rodent studies is endless, there is no predefined program. Transonic’s perivascular flow probes have been around for 30 years. This means that there is no blood vessel that we have not worked with. Let us know what your goals are and we will create a program for you. Who Should Attend: This course is designed for scientists and technicians who are both new to rodent pressure and blood flow recording techniques as well as those who are experienced and wish to refine their techniques. While the course language will be English, the course instructors are also versed in Dutch, German, Spanish and basic French. Therefore, one-to-one instruction can take place in multiple languages. Read the brochure for full details and schedule. Course Directors: Astrid Haegens is a PhD with an all round biomedical laboratory background. Astrid’s expertise is in the field of rodent cardiovascular and pulmonary disease models. She has extensive microsurgery experience and has taught many in-person and videoconference-based microsurgical training sessions. She brings 10 years of academic laboratory experience to Transonic. For the past 9 years, she has been sharing her expertise with Transonic’s customers, to ensure they get the most out of their research. René Remie, PharmD, DLAS, PhD, author and editor of the Manual of Microsurgery on the Laboratory Rat, studied Pharmacy at the University …

Transonic and RRSSC co-organize the fourth 3-4 days practical course on PV-Loops in rats and mice

Rene Remie News

Transonic, René Remie Surgical Skills Centre (RRSSC) and emka TECHNOLOGIES have joined forces and are excited to present the fourth European Rodent, PV Loop & Cardiac Disease Model Workshop. The Workshop is designed to enable attendees to not only optimize their microsurgical skills, but also gain experience in Admittance-based PV measurements, and be introduced to common cardiac disease models. We have designed this course for scientists and technicians who are new to rodent pressure-volume recording techniques or those who would like to refine their techniques. The course will be from October 31- November 2, 2022, with one optional extra day (November 3, 2022) for the induction of cardiac models (LAD occlusion and TAC). Interested? Here is some extra information. If you want to see the program or register for this course click here.

DSI workshop on surgical training for rodent telemetry

Rene Remie Geen categorie

This training is aimed at participants who want to develop surgical skills in implanting telemetric transmitters. It requires a degree as a lab technician, veterinarian, biologist, pharmacologist or any other medical science.We recognize that a critical component to the success of collecting accurate physiological measurements via telemetry is surgical proficiency. Quality surgical training dramatically shortens the learning curve for device implantation and provides earlier success in collecting accurate data. To that end, Data Sciences International (DSI) in collaboration with the René Remie Surgical Skills Centre (RRSSC) proposes a surgical training workshop at the RRSSC. The workshop has a maximum of 8 participants. The training lasts 2 days (14 hours). Click here for additional information and registration

DSI and RRSSC organize an iPRECIO training for SC, IP and IV administration in mice and rats

Rene Remie Geen categorie

DSI and RRSSC offer 3-days training in the implantation of iPRECIO refillable and programmable infusion pumps on April 6-8, 2022 iPRECIO pumps can be completely implanted in small laboratory animals subcutaneously. Thus, the animal moves freely without any restraint (i.e. tethering) during drug infusion. Additionally, infection risk is reduced, and the animal is likely to be significantly less stressed than in a tethered infusion model. You can replenish any medical fluid in the pump via percutaneous access to the pump refill septum and reservoir after implantation of the pump. Therefore, long-term drug infusion can continue until the installed battery life has run out. The reservoir is elastic and configured in such a geometry as to allow gentle palpation to confirm an approximate level of fluid in the reservoir. Wireless programming allows all pumps to be conveniently detected, assigned, programmed and monitored via our IMS-310R iPRECIO Management system. Once completely programmed wirelessly, the iPRECIO SMP-310R Pumps will independently infuse as programmed until completed or aborted without further communications with the IMS-310R. The programmable feature will make iPRECIO® pumps indispensable for applications where accurate flow infusion, recovery/washout periods, constant/variable dose or complex circadian infusion studies are necessary. SMP-310R Pump’s Structure for mice For rats, The SMP-200 pump is available with the following specifications: The battery life is up to 6 months at a flow rate of 1.0μL/hr continuously.You can confirm the estimated battery life on the PC screen when you set the infusion protocol with the iPRECIO Management Software. Flow Rate Infusion Time Total Volume Time (h) days (approx) 30.0μL/hr 196 hr 1 week 5.8 ml 19.0μL/hr 307 hr 1.8 weeks 5.8 ml 8.5μL/hr 669 hr 1 Month 5.6 ml 1.0μL/hr 4,328 hr 6 Months 4.3 ml Do you want to see more? Have a look here. Interested in the training? Please fill …

RRSSC starts courses with NeuroLux wireless optogenetic implants in rats and mice

Rene Remie News

Breakthrough Technologies for Optogenetics At RRSSC we were impressed by the battery-free lightweight ultra miniaturized implantable optogenetics modules. The Neurolux devices are fully implantable and ultra-lightweight. The flexible light sources operate wirelessly across nearly any experimental environment with user-definable pulse frequencies and durations. The system can be configured to meet the needs of many different circumstances. The complete system comes with a laptop, user-friendly GUI, and an initial set of disposable implants.  Conduct studies in freely behaving subjects NeuroLux system provides invasive tools with no external antennas, batteries, fibre optic cables, or head mount. In addition, the implants have an ultra-lightweight construction (0.02 g), which allows subjects to move naturally as individuals or as interacting members of social groups. With the wireless battery-free operation, NeuroLux implants have unlimited operational lifetimes. In addition, the thin, flexible form factors allow the device to affix on top of the subject’s skull for up to fourteen months. Implantation procedure For surgical implantation, optimal stereotaxic techniques and knowledge of good surgical practice are needed. Next to that, a number of special instruments have been designed by the Neurolux Team to optimize implantation whilst minimizing damage to the implant. We are in the process of setting up a three-day training at RRSSC. We will keep you posted.

COVID-19 update

Rene Remie News

Dear customs, March 27, 2022 In The Netherlands, the COVID-19 rules have been completely lifted. We hope to welcome you soon. Until then, stay safe and healthy !! P.S. In case you urgently need training, you could benefit from our online individual training setup. Interested? Ask for more information here.

RRSSC enters strategic partnership with InsideScientific

Rene Remie Geen categorie

Since WHO declared Covid-19 a pandemic, RRSSC has observed the resulting drastic changes to research and how now, more than ever, it has become increasingly important to be able to plan, scale and create animal models that efficiently deliver meaningful findings. To reach our goal of making in-lab and virtual training programs accessible to more researchers, we are gratified to announce our agreement with InsideScientific, an online environment of resources for life-science researchers. We will be collaborating on new virtual and in-lab training programs. For example, RRSSC recently provided important scientific content for a live online demo session on inhalation anaesthesia for one of Kent’s major European customers. We both look forward to continuing cultivating our relationship. The new alliance is part of our strategy to enable more labs to gain the skills and confidence to accelerate their research designs, improve results, and transfer critical skills to other lab members – this is particularly important as surgical skills play a crucial role in research success and reproducibility of quality data. In addition, by offering improved access to advanced techniques, we believe that scientists will gain an increased understanding of physiological systems and associated diseases and become more optimally equipped to develop effective treatments. InsideScientific founding director Andy Henton remarks, “Together, we will support the global research community and ensure scientists have the critical surgical skills and vision they need to explore and discover new areas of physiology and medicine.”

!!NEW!! Online (micro)surgical training at RRSSC

Rene Remie Geen categorie

Online (micro)surgical training at RRSSC (download the PDF) At the René Remie Surgical Skills Centre (RRSSC) training facilities in Almere, The Netherlands, we have trained many surgeons, veterinarians, animal technicians, and scientists. We teach the general principle of surgery in rodents and provide training in a large number of specific (micro)surgical procedures such as catheterizations for chronic blood sampling, implantation of devices, and experimental techniques. The dedicated surgical workstations, personal attention, and relaxed atmosphere during our courses create the ideal circumstances for knowledge transfer. Our website testimonials speak for themselves  (https://www.rrssc.eu/testimonials-2/). Like many other businesses, we are affected by the travel restrictions of our clients due to the Corona pandemic and subsequently, the number of course participants being able to follow our training modules has decreased. Despite the challenges of reduced travelling, we continue to offer hands-on surgery training at our facilities in Almere, The Netherlands. Although we believe that surgical training is best achieved with personal guidance in our dedicated training facilities, we have, after a request from Transonic, decided to set up online surgical training for advanced surgeons and thus expand our training possibilities. With online surgical training, we continue to comply with our mission “To share our experience and enthusiasm for setting and achieving ambitious levels of surgical skills”. This means we have set the highest standard for performing this online surgical training. Both the microscope-vision and overview of the surgical area are provided. Additionally, we offer the possibility to monitor you while performing surgery, using a portable digital microscope. This allows us to guide you through procedures and help you perform difficult steps in the operation. The online communication using Microsoft Teams enables us to invite other specialists in our network to assist. The training sessions are recorded for future reference. Like any surgery, online surgical …